Oriana Miltiadous, MD
Clinical Instructor, Pediatric Department
Senior Research Scientist, van den Brink laboratory - Microbiota Group
Education
MD, University of Athens Medical School (2011)
Fellowships
Pediatric Hematology/Oncology, Memorial Sloan Kettering Cancer Center – New York Presbyterian/Weill Cornell Medical Center (2020)
Residencies
Intern in pediatrics, Miami Children’s Hospital
Resident in pediatrics, Miami Children’s Hospital
Board Certifications
Pediatrics
Biography
Oriana is a Clinical Instructor in the Department of Pediatrics/MSK Kids while conducting research in microbiome and correlates with outcomes of patients with cancer and other life-threatening conditions in the van den Brink Laboratory.
Oriana received her medical degree from the University of Athens in 2011. She then worked with Drs. Josep Llovet and Scott Friedmann at the Icahn School of Medicine at Mount Sinai and published her research and collaborative projects on identifying biomarkers for liver cancer in three high-impact journals, namely, the Journal of Hepatology, Nature, and Nature Communications. She completed her general pediatric training at Miami Children’s Hospital in 2017 and then joined the pediatric hematology/oncology fellowship program at Memorial Sloan Kettering Cancer Center and New York Presbyterian–Weill Cornell Medical Center.
She developed her research projects on microbiome with mentoring from Shakeel Modak, Eric Pamer, Jaap Jan Boelens, Susan Prockop, and Marcel van den Brink. In 2020, she received the Young Investigator Award from the American Society of Clinical Oncology (ASCO) and Hyundai Hope on Wheels. She was awarded the Michael Goldberg fellowship in 2021 and more recently, in 2022 she received the Career Development Award from the Tow Center for Developmental Oncology.
Research
My research is currently focused on two areas:
Microbiome and outcomes after hematopoietic transplantation. Our group previously published that gut microbiome is associated with mortality and graft vs host disease after hematopoietic transplantation. I am investigating this link by further exploring the relationship between microbiota composition and immune recovery as well as the microbiota metabolites and their effects on the incidence of graft vs host disease. Our work was published by Blood (Miltiadous O et al 2022) and was presented in several meetings (Transplantation & Cellular Therapy Meetings, Coldspring Harbor – microbiome meeting, American Society of Hematology).
I am also exploring the links of microbiota with outcomes of pediatric cancer patients. I am evaluating how microbiome composition affects remission rates in pediatric patients with neuroblastoma undergoing therapy and how is this affecting long term outcomes.
Funding and Awards
American Society of Pediatric Hematology/Oncology Young Investigator Award (2023)
Tow Center for Developmental Oncology Career Development Award (2022)
Cycle for Survival Innovative Award (co-PI; PI: Jaap Jan Boelens)
Michael Goldberg Fellowship (2021)
American Society of Clinical Oncology – Young Investigator Award (2020)
Collaborative Pediatric Research Program Award – Batcole foundation (2020)
Hyundai Hope on Wheels – Young Investigator Award (2020)
End Kids Cancer Grant (2019)
Member, American Society of Pediatric Hematology/Oncology (ASPHO)
Member, American Association of Cancer Research (AACR)
Member, American Academy of Pediatrics (AAP)
Member, American Society of Clinical Oncology (ASCO)
Member, Children’s Oncology Group (COG)